Type of Project
Total marks = 50 (15%)
(A trial-based Economic evaluation study)
Instructions for preparing and submitting the assignment
alongside a randomized controlled trial (RCT), using a published study from the
answering these questions
they will read, learn and practice at home and prepare the assignment.
required to answer these question.
“A cost effectiveness analysis within a randomised controlled trial of
post-acute care of older people in a community hospital” by Jacqueline O’Reilly,
Karin Lowson, John Young, Anne Forster, John Green, Neil Small, BMJ,
Question -1: (3+1+2=6 marks)
yes or no, justify your answer
Question -2: (7×2= 14 marks)
Identify and briefly describe briefly the following PICO terms of the cost-effectiveness analysis
in the study.
Duration of the Economic Evaluation
No. of patients randomized to ‘Intervention’ group__________________________________
No. of patients randomized to ‘Control’ group ______________________________________
Question -3: (5+ 2+ 3=10 marks)
Quality Adjusted Life Year, QALY) data were captured in the study
Question -4: (4+3+3= 10 marks)
In Table 1, the study shows that, from ‘all patients’ analysis the average observed QALY over 6
months study period in the community hospital group is 0.38 and the observed QALY in the
district hospital group is 0.35. However, the difference (95% CI) in QALY over 6 months
between two groups is 0.06 (-0.05 to 0.18).
analyses – ‘all patients’ and ‘surviving patients’?
iii) Is the difference in QALY between two treatment groups statistically significant or not?
Justify your answer in TWO sentences.
Question -5: (2+4 + 2+1 +1=10 marks)
months study period between two options, and indicate which treatment option is more
cost-effective in the ‘base case’ cost-effectiveness analysis and why (state in THREE
from the ‘base case’ analysis?
representing the sensitivity analysis in probability term. If the policy makers is willing to
pay (WTP) £10000 per QALY, then what is the probability that community hospital care
would be more cost-effective than district hospital care?
decrease in probability that community hospital care would be more cost-effective than
district hospital care – TRUE or FALSE
PUBH 430 Health Economics Assignment